FlyBase Allele Report: Dmel\RluA-1[del-HDR]

General Information

Symbol

Dmel\RluA-1^del-HDR

Species

D. melanogaster

Name

FlyBase ID

FBal0365306

Feature type

allele

Associated gene

Dmel\RluA-1

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Song et al., 2020)

Mutagen

CRISPR/Cas9

(Song et al., 2020)

recombination

(Song et al., 2020)

Progenitor genotype

Cytology

Description

A precise genetic deletion of RluA-1 in which 11.14 kbp, including the entire RluA-1 genomic region, is removed.

(Song et al., 2020)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2L:10,463,281..10,474,420 [-]

(Song et al., 2020)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage

(Song et al., 2020)

abnormal pain response | larval stage

(Song et al., 2020)

abnormal pain response | larval stage (with RluA-1^del-FRT)

(Song et al., 2020)

Phenotype Manifest In

dendritic branch | increased number | larval stage

(Song et al., 2020)

larval dorsal multidendritic neuron ddaC

(Song et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

RluA-1^del-HDR has abnormal pain response | larval stage phenotype, suppressible | partially by RluA-2^del-HDR/RluA-2^del-HDR

(Song et al., 2020)

NOT Enhancer of

Statement

Reference

RluA-1^del-HDR/RluA-1^del-HDR is a non-enhancer of abnormal pain response | larval stage phenotype of RluA-2^del-HDR

(Song et al., 2020)

NOT Suppressor of

Statement

Reference

RluA-1^del-HDR/RluA-1^del-HDR is a non-suppressor of abnormal pain response | larval stage phenotype of RluA-2^del-HDR

(Song et al., 2020)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

RluA-1^del-HDR is rescued by RluA-1^UAS.cSa/Scer\GAL4^ppk.1.9

(Song et al., 2020)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

RluA-1^del-HDR

(Song et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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