FB2025_01 , released February 20, 2025
Allele: Hsap\TGFB3UAS.cNa
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General Information
Symbol
Hsap\TGFB3UAS.cNa
Species
H. sapiens
Name
FlyBase ID
FBal0373516
Feature type
allele
Associated gene
Hsap\TGFB3
Associated Insertion(s)
Carried in Construct
PBac{UAS-hTGFB3.N}
Key Links
Transgenic product class
cDNA
(Fourth Chromosome Resource Project and Newfeld, 2022-)
wild_type
(Fourth Chromosome Resource Project and Newfeld, 2022-)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Fourth Chromosome Resource Project and Newfeld, 2022-)
wild_type
(Fourth Chromosome Resource Project and Newfeld, 2022-)
Mutagen
in vitro construct
(Fourth Chromosome Resource Project and Newfeld, 2022-)
Progenitor genotype
Carried in construct
PBac{UAS-hTGFB3.N}
Cytology
Description

UASt regulatory sequences drive expression of the Hsap\TGFB3 open reading frame. The endogenous stop codon is present, thus even though three copies of the Tag:HA tag are present downstream of the ORF, they are not expected to form part of the translated protein. The ORF is flanked by a pair of incompatible FRT sites (FRT5 and FRT2), which allows for future in vivo exchange of either the promoter or tag sequence.

(Fourth Chromosome Resource Project and Newfeld, 2022-)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\TGFB3
Also carries
FRT2
FRT5
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hsap\TGFB3UAS.cNa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)