FB2025_01 , released February 20, 2025
Gene Group: RAP-LIKE GTPASE ACTIVATING PROTEINS
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General Information
Name
RAP-LIKE GTPASE ACTIVATING PROTEINS
Species
D. melanogaster
Symbol
RAPGAP
FlyBase ID
FBgg0000327
Date last reviewed
2015-08-06
Number of members
4
Description
Description
Rap-like GTPase activating proteins (RapGAP) are an evolutionary-related group of RasGAPs that promote GTP hydrolysis by either Ral, Rap or Rheb subfamilies of the Ras GTPases. (Adapted from FBrf0229300).
Notes on Group

CG34408 (orthologous to human RalGAPB, a non-catalytic subunit) has been excluded as it is not thought to have GAP activity (FBrf0229300).

Source Material
The RAP-LIKE GTPASE ACTIVATING PROTEINS Gene Group has been compiled using the following publication(s): Diez et al., 2011, van Dam et al., 2011, Bernards, 2003, and Zhang et al., 2003 .
Key Gene Ontology (GO) terms
Molecular Function
GTPase activator activity
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
RAS GTPASE ACTIVATING PROTEINS
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG5521
(Diez et al., 2011, van Dam et al., 2011, Bernards, 2003)
gig
gigas
TSC2, dTsc2, l(3)109
(Diez et al., 2011, van Dam et al., 2011, Bernards, 2003, Zhang et al., 2003)
RapGAP1
Rap GTPase activating protein 1
RapGAP
(Diez et al., 2011, van Dam et al., 2011, Bernards, 2003)
rsh
rsh GTPase activating protein
radish, rad
(Diez et al., 2011, van Dam et al., 2011, Bernards, 2003)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
RAPGAP
Rap-GAP
Ral-GAP
Rheb-GAP
TSC2 GAP
RAP-LIKE GTPASE ACTIVATING PROTEINS
Rap GAP domain-containing
Secondary FlyBase ID(s)
References (5)