FB2025_01 , released February 20, 2025
Gene Group: RAD51-LIKE ATPASES
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General Information
Name
RAD51-LIKE ATPASES
Species
D. melanogaster
Symbol
RAD51
FlyBase ID
FBgg0001597
Date last reviewed
2020-07-08
Number of members
5
Description
Description
Rad51-like ATPases include RAD51 and its paralogs, which play an essential role in repair of double-strand DNA breaks through homologous recombination. They act to transduce the DNA damage signal to effector kinases and to promote break repair. (Adapted from PMID:21821141.)
Notes on Group
Source Material
The RAD51-LIKE ATPASES Gene Group has been compiled using the following publication(s): Sekelsky, 2017 and Sekelsky et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
ATP-dependent DNA damage sensor activity
Biological Process
DNA recombination
Cellular Component
Related Gene Groups
Parent group(s)
ATP-DEPENDENT DNA DAMAGE SENSORS
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Rad51D
Rad51 recombinase D
Rad51C
(FlyBase, 2017-, Sekelsky, 2017, Sekelsky et al., 2000)
spn-A
spindle A
spnA, Rad51, DmRad51, DMR
(FlyBase, 2017-, Sekelsky, 2017, Sekelsky et al., 2000)
spn-B
spindle B
spnB, XRCC3
(FlyBase, 2017-, Sekelsky, 2017, Sekelsky et al., 2000)
spn-D
spindle D
spnD
(FlyBase, 2017-, Sekelsky, 2017)
Xrcc2
X-ray repair cross complementing 2
Rad51D
(FlyBase, 2017-, Sekelsky, 2017, Sekelsky et al., 2000)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
RAD51
RAD51-LIKE ATPASES
Secondary FlyBase ID(s)
References (4)