FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Tip60, E(Pc)
FlyBase ID
FBig0000097509
Interaction Network
Interactions Browser links
Tip60 network
E(Pc) network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0185742-31.PD.WB
Reference
Kusch et al., 2004
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Tip60 

dTip60

bait
E(Pc) 

E(Pc)

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Kusch et al., 2004)
FBrf0259561-4.PD.MW
Reference
Kiss et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Tip60 

Tip60

bait

Strep tag

E(Pc) 

E(Pc)

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait and prey produced as a recombinant fusion protein in baculovirus and insect cell system.

(Kiss et al., 2024)

Tip60, E(Pc) and Ing3 (dTip60-piccolo complex) were cloned into a single vector and affinity purified. Captured as 3 pairwise interactions utilizing strep-tagged Tip60 as bait.

(Kiss et al., 2024)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)