FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
TBPH, N
FlyBase ID
FBig0000106658
Interaction Network
Interactions Browser links
TBPH network
N network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0233521-2.PD.PCR
Reference
Swain et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
TBPH 

TBPH

bait

His tag

TBPH 
N 

Notch

prey
N 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
TBPH 
RRM1
sufficient binding region
aa 1-190

coordinates relative to TBPH-PB

N 
region 1
sufficient binding region
AGUGGUGUACAGUGGUCACUCAUUCAUAUUGUAUGUGUGUGUGUGUGUGUAUCGGCGUUC

"Notch-1" construct

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro transcription.

(Swain et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)