FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
TER94, Mer
FlyBase ID
FBig0000116881
Interaction Network
Interactions Browser links
TER94 network
Mer network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0224345-140.coIP.MS
Reference
Kwon et al., 2013
Description
physical association
Assay
Collection
Hippo_Pathway_Interactome
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
Mer 

Mer

bait

Protein A tag, Strep tag

TER94 

TER94

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2R+ cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Kwon et al., 2013)
FBrf0259436-1.coIP.WB
Reference
Li et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
TER94 

Ter94

bait

Fg tag

TER94 
TER94 
Mer 

Mer

prey

Myc tag

Mer 
Mer 
Mer 
Mer 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
TER94 
N-terminal domain
sufficient binding region
aa 1-210

coordinates relative to TER94-PA

TER94 
C-terminal domain
sufficient binding region
aa 661-801

coordinates relative to TER94-PA

Mer 
FERM domain residue 36
mutation decreasing interaction
aa 36

L36R; coordinates relative to Mer-PA

Mer 
FERM domain residue 52
mutation decreasing interaction
aa 52

F52S; coordinates relative to Mer-PA

Mer 
FERM domain residue 54
mutation decreasing interaction
aa 54

L54P; coordinates relative to Mer-PA

Mer 
FERM domain residue 135
mutation decreasing interaction
aa 135

L135P; coordinates relative to Mer-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK-293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Li et al., 2024)
FBrf0259436-2.coIP.WB
Reference
Li et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Mer 

Mer

bait

Myc tag

Mer 
TER94 

Ter94

prey

Fg tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Mer 
FERM domain
sufficient binding region
aa 1-300

coordinates relative to Mer-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK-293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Li et al., 2024)
External Crossreferences and Linkouts ( 0 )
References (2)