FB2025_01 , released February 20, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
AP-1-2β, Arr2
FlyBase ID
FBig0000119721
Interaction Network
Interactions Browser links
AP-1-2β network
Arr2 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0191981-1.PD.WB
Reference
Orem et al., 2006
Description
physical association
Assay
Collection
Source/Stage
head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AP-1-2β 

AP-2β

bait

MBP tag

AP-1-2β 
Arr2 

Arr2

prey
Arr2 
Arr2 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
AP-1-2β 
EAR domain
sufficient binding region
aa 743-921
Arr2 
C-terminal domain residue 391
mutation disrupting interaction
aa 391

K391A

Arr2 
C-terminal domain residue 393
mutation disrupting interaction
aa 393

R393A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type or transgenic adult head extract.

(Orem et al., 2006)
External Crossreferences and Linkouts ( 0 )
References (1)