A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Layalle, S., Coessens, E., Ghysen, A., Dambly-Chaudiere, C. (2005). Smooth, a hnRNP encoding gene, controls axonal navigation in Drosophila.  Genes Cells 10(2): 119--125. (Export to RIS)
FlyBase ID FBrf0183990
Publication Type Research paper
PubMed ID 15676023
PubMed Abstract We identified the gene smooth (sm) in a screen for genes that are specifically expressed within the lineage that forms the adult chemosensory bristles. sm is expressed in most or all differentiating neurones during embryogenesis, but is specifically expressed in the neurones of the adult chemosensory organs on the wings and legs during metamorphosis. The inactivation of sm results in axonal defects in the chemosensory neurones, in the inability of mutant flies to feed and in their precocious death. As sm belongs to a family of heterogeneous nuclear ribonucleoprotein (hnRNP), we propose that the control of axonal navigation and connectivity is partly achieved at the level of mRNA splicing or exporting.
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Language of Publication English
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Publication Type Journal
Abbreviation Genes Cells
Title Genes to cells : devoted to molecular & cellular mechanisms
Publication Year 1996-
ISBN/ISSN 1356-9597
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