FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term MCD diffuse large B-cell lymphoma ID (Ontology) DOID:0081066 (Human Disease)
Definition A diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding.
Also Known As "MCD DLBCL"
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  large B-cell lymphoma
   |__diffuse large B-cell lymphoma
       |__MCD diffuse large B-cell lymphoma
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Is a diffuse large B-cell lymphoma
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Synonyms
  • "MCD DLBCL" EXACT OMO:0003012
Secondary IDs
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NCI:C148394