FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protocerebrum ID (Ontology) FBbt:00003627 (Fly Anatomy)
Definition The most anterior neuromere of the central nervous system, developing from neuroblasts of the labral and ocular segments (Urbach and Technau, 2003; Ito et al., 2014). The protocerebrum comprises many discrete neuropil regions including the central complex and mushroom bodies (Ito et al., 2014).[ FlyBase:FBrf0161020 FlyBase:FBrf0224194 ]
Also Known As "PR" ; "protocerebral neuromere"
Comment Urbach and Technau (2003) divide the protocerebrum into labral and ocular neuromeres.
Links to External Ontologies
VFB:FBbt_00003627
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      13
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      16
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       1
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles  Genes Images Insertions Constructs
 protocerebrum (all annotations which use CV term, excluding "NOT" statements)      13      1     17      2     17      9
     protocerebrum | adult stage       2       --       --       --       --       2
     protocerebrum | dorsal       1       --       --       --       --       --
     protocerebrum | RU486 conditional       2       --       --       --       --       2
     protocerebrum | somatic clone       3       --       --       --       --       --
Spanning Tree (Parents/Children)
Only view relationship: 
supraesophageal ganglion
 |__supraesophageal zone_______________
central nervous system                 |
 |__neuromere__________________________|
segmental subdivision of organ system  |
 |__neuromere__________________________|
multicellular structure                |
 |__supraesophageal zone_______________|
                                       protocerebrum  12262 rec.
                                        |__adult protocerebral SMP Tachykinin neuron 4 rec.
                                        |__adult protocerebrum 11235 rec.
                                        |   |__adult central complex(+) 3519 rec.
                                        |   |__adult great commissure 4 rec.
                                        |   |__adult lateral ellipsoid fascicle(+)
                                        |   |__adult lateral horn 1972 rec.
                                        |   |__adult middle dorsal commissure
                                        |   |__adult mushroom body(+) 5808 rec.
                                        |   |__adult optic lobe(+) 5766 rec.
                                        |   |__adult posterior lateral fascicle(+)
                                        |   |__adult posterior superior transverse fascicle(+)
                                        |   |__adult sub-ellipsoid commissure
                                        |   |__anterior optic tubercle(+) 3094 rec.
                                        |   |__broad root
                                        |   |__cell body rind of adult protocerebrum(+) 272 rec.
                                        |   |__inferior neuropils(+) 4404 rec.
                                        |   |__lateral medial fascicle 3 rec.
                                        |   |__medial fascicle
                                        |   |__superior intermediate protocerebrum(+) 3770 rec.
                                        |   |__superior lateral protocerebrum(+) 4855 rec.
                                        |   |__superior medial protocerebrum(+) 4605 rec.
                                        |__embryonic protocerebrum 56 rec.
                                        |   |__anterior protocerebral neuromere 7 rec.
                                        |   |__central protocerebral neuromere
                                        |   |__posterior protocerebral neuromere 1 rec.
                                        |   |__protocerebral embryonic fiber tract(+)
                                        |   |__protocerebral embryonic fiber tract founder cluster(+) 1 rec.
                                        |__larval protocerebrum 1215 rec.
                                        |   |__bulb primordium(+)
                                        |   |__cell body rind of larval protocerebrum(+) 9 rec.
                                        |   |__embryonic/larval lateral accessory lobe
                                        |   |__embryonic/larval mushroom body(+) 285 rec.
                                        |   |__embryonic/larval optic lobe(+) 939 rec.
                                        |   |__embryonic/larval posterior lateral protocerebrum(+)
                                        |   |__embryonic/larval protocerebral commissure
                                        |   |__embryonic/larval ventrolateral protocerebrum
                                        |   |__larval anterior transverse tract
                                        |   |__larval inferior protocerebrum(+) 2 rec.
                                        |   |__larval posterior superior transverse fascicle(+)
                                        |   |__larval sub-ellipsoid commissure
                                        |   |__larval superior protocerebrum(+) 2 rec.
                                        |__mushroom body 6112 rec.
                                        |   |__adult mushroom body(+) 5808 rec.
                                        |   |__embryonic/larval mushroom body(+) 285 rec.
                                        |   |__mushroom body neuropil subdivision(+) 3022 rec.
                                        |__posterior superior transverse fascicle
                                        |   |__adult posterior superior transverse fascicle(+)
                                        |   |__larval posterior superior transverse fascicle(+)
                                        |   |__lateral posterior superior transverse fascicle(+)
                                        |   |__medial posterior superior transverse fascicle(+)
                                        |__protocerebral neuroblast 175 rec.
                                        |   |__anterior protocerebral neuroblast(+) 7 rec.
                                        |   |__central protocerebral neuroblast(+) 13 rec.
                                        |   |__neuroblast BAmd1(+)
                                        |   |__neuroblast BAmv1
                                        |   |__neuroblast BLAd5
                                        |   |__neuroblast BLAl1
                                        |   |__neuroblast BLAl2
                                        |   |__neuroblast BLAvm
                                        |   |__neuroblast BLD1
                                        |   |__neuroblast BLD2
                                        |   |__neuroblast BLD3
                                        |   |__neuroblast BLD4
                                        |   |__neuroblast BLD5
                                        |   |__neuroblast BLD6
                                        |   |__neuroblast BLP1
                                        |   |__neuroblast BLP2
                                        |   |__neuroblast BLP4
                                        |   |__neuroblast BLVa1
                                        |   |__neuroblast BLVa2
                                        |   |__neuroblast BLVa2a
                                        |   |__neuroblast BLVa2b
                                        |   |__neuroblast BLVa2c
                                        |   |__neuroblast BLVp1
                                        |   |__neuroblast BLVp2
                                        |   |__neuroblast CP4
                                        |   |__neuroblast CP6
                                        |   |__neuroblast DALcl1
                                        |   |__neuroblast DALcl2
                                        |   |__neuroblast DALl2
                                        |   |__neuroblast DALv1
                                        |   |__neuroblast DALv3
                                        |   |__neuroblast DAMd1
                                        |   |__neuroblast DPL(+) 1 rec.
                                        |   |__neuroblast DPM(+)
                                        |   |__neuroblast LHa4
                                        |   |__neuroblast MBp(+) 61 rec.
                                        |   |__neuroblast SLPal4
                                        |   |__neuroblast SLPpm4
                                        |   |__neuroblast SMPad1(+)
                                        |   |__neuroblast SMPad2
                                        |   |__neuroblast SMPad4
                                        |   |__neuroblast VLPl1
                                        |   |__neuroblast VPNd2
                                        |   |__neuroblast VPNd3
                                        |   |__neuroblast VPNd4
                                        |   |__neuroblast VPNp2
                                        |   |__neuroblast VPNp3
                                        |   |__neuroblast VPNv1
                                        |   |__neuroblast VPNv2
                                        |   |__neuroblast VPNv3
                                        |   |__optic neuroblast(+) 85 rec.
                                        |   |__posterior protocerebral neuroblast(+) 12 rec.
                                        |__sub-ellipsoid commissure
                                            |__adult sub-ellipsoid commissure
                                            |__larval sub-ellipsoid commissure
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Is a neuromere
Part of supraesophageal zone
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Synonyms
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UBERON:6003627
VFB:FBbt_00003627