FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term medulla ID (Ontology) FBbt:00003748 (Fly Anatomy)
Definition The second optic neuropil, sandwiched between the lamina and the lobula complex. It is divided into 10 layers: 1-6 make up the outer (distal) medulla, the seventh (or serpentine) layer exhibits a distinct architecture and layers 8-10 make up the inner (proximal) medulla (Ito et al., 2014).[ FlyBase:FBrf0224194 FlyBase:FBrf0231227 ]
Also Known As "ME" ; "Med" ; "optic medulla"
Comment Nern et al. (2025) - FBrf0262545 say distal is M1-5 and M6-7 is central medulla.
Links to External Ontologies
VFB:FBbt_00003748
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     213
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      95
Insertions (FBti)  PHENOTYPE_MANIFEST_IN      37
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      91
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 medulla (all annotations which use CV term, excluding "NOT" statements)     213      2     82    132   2400
     medulla | adult stage      24       --       --       2     16
     medulla | adult stage | progressive       1       --       --       1       --
     medulla | adult stage | somatic clone       1       --       --       --       --
     medulla | distal       2       --       --       1       --
     medulla | heat sensitive       3       --       --       --       4
     medulla | larval stage      17       --       --       --      12
     medulla | larval stage | somatic clone       9       --       --       --       7
     medulla | P-stage      27       --       --       7      8
     medulla | P-stage | somatic clone       8       --       --       --       5
     medulla | pharate adult stage       2       --       --       --       1
     medulla | progressive       2       --       --       --       2
     medulla | proximal       1       --       --       1       --
     medulla | pupal stage       5       --       --       --       2
     medulla | pupal stage | somatic clone       1       --       --       --       --
     medulla | somatic clone      23       --       --       3      2
     medulla | third instar larval stage      16       --       --       5      7
Spanning Tree (Parents/Children)
Only view relationship:
multi-tissue structure
 |__adult optic lobe______________
multi-cell-component structure    |
 |__synaptic neuropil domain______|
adult protocerebrum               |
 |__adult optic lobe______________|
ectodermal derivative             |
 |__anterior ectoderm derivative__|
synaptic neuropil                 |
 |__synaptic neuropil domain______|
visual system                     |
 |__adult optic lobe______________|
adult primary visual center       |
 |__adult optic lobe______________|
                                  medulla  2939 rec.
                                   |__adult medulla neuropil associated glial cell 28 rec.
                                   |   |__adult medulla astrocyte-like glial cell(+) 2 rec.
                                   |   |__adult medulla ensheathing glial cell(+) 2 rec.
                                   |   |__distal medulla glial cell(+) 2 rec.
                                   |__medulla layer 129 rec.
                                       |__inner medulla(+) 21 rec.
                                       |__medulla dorsal rim area
                                       |__medulla layer M1 24 rec.
                                       |__medulla layer M2 19 rec.
                                       |__medulla layer M3(+) 42 rec.
                                       |__medulla layer M4 4 rec.
                                       |__medulla layer M5 8 rec.
                                       |__medulla layer M6(+) 32 rec.
                                       |__medulla layer M8 6 rec.
                                       |__medulla layer M9 6 rec.
                                       |__medulla layer M10 10 rec.
                                       |__medulla serpentine layer 12 rec.
                                       |__medulla sublayer M3A
                                       |__medulla sublayer M3B
                                       |__medulla sublayer M6A
                                       |__medulla sublayer M6B
                                       |__outer medulla(+) 111 rec.
                                       |__plexiform medulla(+) 111 rec.
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Is a anterior ectoderm derivative
synaptic neuropil domain
Develops from medulla anlage
Part of adult optic lobe
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Synonyms
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VFB:FBbt_00003748