FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term urea cycle ID (Ontology) GO:0000050 (Gene Ontology)
Definition The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.[ ISBN:0198506732 ]
Also Known As "ornithine cycle" ; "urea biosynthesis" ; "urea biosynthetic process"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
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 Genes
 urea cycle (all annotations which use CV term, excluding "NOT" statements)       2
     involved_in | urea cycle       2
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biosynthetic process
 |__amide biosynthetic process____
amide metabolic process           |
 |__urea metabolic process________|
 |__amide biosynthetic process____|
small molecule metabolic process  |
 |__urea metabolic process________|
nitrogen cycle metabolic process  |
 |__urea metabolic process________|
                                  urea cycle  2 rec.
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Is a urea metabolic process
amide biosynthetic process
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Synonyms
  • "ornithine cycle" EXACT
    "urea biosynthesis" EXACT
    "urea biosynthetic process" EXACT
Secondary IDs
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Reactome:R-HSA-70635 "Urea cycle"
Wikipedia:Urea_cycle