FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term G1/S transition of mitotic cell cycle ID (Ontology) GO:0000082 (Gene Ontology)
Definition The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      17
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 Genes
 G1/S transition of mitotic cell cycle (all annotations which use CV term, excluding "NOT" statements)      17
     involved_in | G1/S transition of mitotic cell cycle      17
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cell cycle phase transition
 |__mitotic cell cycle phase transition__
 |__cell cycle G1/S phase transition_____|
mitotic cell cycle process               |
 |__mitotic cell cycle phase transition__|
                                         G1/S transition of mitotic cell cycle  40 rec.
                                          |__regulation of G1/S transition of mitotic cell cycle 27 rec.
                                              |__negative regulation of G1/S transition of mitotic cell cycle(+) 15 rec.
                                              |__positive regulation of G1/S transition of mitotic cell cycle(+) 11 rec.
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Is a mitotic cell cycle phase transition
cell cycle G1/S phase transition
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Reactome:R-HSA-69206 "G1/S Transition"