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General Information
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| Term |
nuclear exosome (RNase complex) |
ID (Ontology) |
GO:0000176 (Gene Ontology) |
| Definition |
A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.[ PubMed:17174896 PubMed:20531386 PubMed:26726035 ] |
| Also Known As |
"eukaryotic exosome multienzyme ribonuclease complex" ; "nuclear exosome (ribonuclease complex)" ; "nuclear exosome multienzyme ribonuclease complex" |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 10 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Gene Groups | Genes |
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nuclear exosome (RNase complex) (all annotations which use CV term, excluding "NOT" statements) | 1 | 10 | part_of | nuclear exosome (RNase complex) | -- | 10 |
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Relationships
