General Information
Term	spliceosomal conformational changes to generate catalytic conformation	ID (Ontology)	GO:0000393 (Gene Ontology)
Definition	Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.
Comment
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General Information

Term

spliceosomal conformational changes to generate catalytic conformation

ID (Ontology)

GO:0000393 (Gene Ontology)

Definition

Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
 |__mRNA splicing, via spliceosome____
mRNA processing                       |
 |__mRNA splicing, via spliceosome____|
ribonucleoprotein complex biogenesis  |
 |__protein-RNA complex assembly______|
protein-containing complex assembly   |
 |__protein-RNA complex assembly______|
protein-RNA complex organization      |
 |__protein-RNA complex assembly______|
                                      spliceosomal conformational changes to generate catalytic conformation  4 rec.
                                       |__generation of catalytic spliceosome for first transesterification step 1 rec.
                                       |__generation of catalytic spliceosome for second transesterification step 2 rec.
                                       |   |__alignment of 3' and 5' splice sites of mRNA
                                       |__spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) 1 rec.

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Is a	protein-RNA complex assembly
Part of	mRNA splicing, via spliceosome
Synonyms & Secondary IDs
Synonyms
	"3'-splice site cleavage, exon ligation" BROAD
Secondary IDs

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Is a

protein-RNA complex assembly

Part of

mRNA splicing, via spliceosome

Synonyms & Secondary IDs

Synonyms

"3'-splice site cleavage, exon ligation" BROAD

Secondary IDs

External Crossreferences & Linkouts