FB2025_05 , released December 11, 2025

CV Term Report

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General Information
Term	RNA splicing, via endonucleolytic cleavage and ligation	ID (Ontology)	GO:0000394 (Gene Ontology)
Definition	Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.[ ISBN:0879695897 ]
Comment
Links to External Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Spanning Tree (Parents/Children)

  RNA processing
   |__RNA splicing
       |__RNA splicing, via endonucleolytic cleavage and ligation  10 rec.
           |__mRNA splicing, via endonucleolytic cleavage and ligation
           |__RNA exon ligation
           |   |__tRNA exon ligation
           |__tRNA splicing, via endonucleolytic cleavage and ligation 10 rec.
               |__tRNA exon ligation
               |__tRNA-type intron splice site recognition and cleavage 3 rec.

Spanning Tree View Settings
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Relationships
Is a	RNA splicing
Part of
Synonyms & Secondary IDs
Synonyms
	"mRNA splicing" BROAD
Secondary IDs

External Crossreferences & Linkouts