FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term L-methionine catabolic process to 3-methylthiopropanol ID (Ontology) GO:0000951 (Gene Ontology)
Definition The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When L-methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.[ PubMed:18281432 ]
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sulfur amino acid catabolic process
 |__L-methionine catabolic process_______________________________
amino acid catabolic process via Ehrlich pathway                 |
 |__amino acid catabolic process to alcohol via Ehrlich pathway__|
methionine metabolic process                                     |
 |__L-methionine catabolic process_______________________________|
sulfur compound metabolic process                                |
 |__sulfur compound biosynthetic process_________________________|
biosynthetic process                                             |
 |__sulfur compound biosynthetic process_________________________|
alcohol biosynthetic process                                     |
 |__amino acid catabolic process to alcohol via Ehrlich pathway__|
L-amino acid catabolic process                                   |
 |__L-methionine catabolic process_______________________________|
proteinogenic amino acid catabolic process                       |
 |__L-methionine catabolic process_______________________________|
                                                                 L-methionine catabolic process to 3-methylthiopropanol
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Is a amino acid catabolic process to alcohol via Ehrlich pathway
L-methionine catabolic process
sulfur compound biosynthetic process
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MetaCyc:PWY-5082