FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term nuclear-transcribed mRNA catabolic process ID (Ontology) GO:0000956 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
Also Known As "nuclear mRNA breakdown" ; "nuclear mRNA catabolism" ; "nuclear mRNA degradation"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      14
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 Genes
 nuclear-transcribed mRNA catabolic process (all annotations which use CV term, excluding "NOT" statements)      14
     involved_in | nuclear-transcribed mRNA catabolic process      14
Spanning Tree (Parents/Children)
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RNA catabolic process___________________
negative regulation of gene expression__|
mRNA metabolic process__________________|
                                        mRNA catabolic process
                                         |__nuclear-transcribed mRNA catabolic process  65 rec.
                                             |__deadenylation-dependent decapping of nuclear-transcribed mRNA 7 rec.
                                             |   |__regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA(+)
                                             |__histone mRNA catabolic process 1 rec.
                                             |   |__nuclear histone mRNA catabolic process
                                             |__nuclear mRNA surveillance 8 rec.
                                             |   |__nuclear mRNA surveillance of meiosis-specific transcripts(+)
                                             |   |__nuclear mRNA surveillance of mRNA 3'-end processing 2 rec.
                                             |   |__nuclear mRNA surveillance of mRNP export 1 rec.
                                             |   |__nuclear mRNA surveillance of spliceosomal pre-mRNA splicing
                                             |__nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 26 rec.
                                             |   |__deadenylation-dependent decapping of nuclear-transcribed mRNA 7 rec.
                                             |   |__nuclear-transcribed mRNA poly(A) tail shortening 17 rec.
                                             |   |__regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(+) 2 rec.
                                             |__nuclear-transcribed mRNA catabolic process, deadenylation-independent decay 6 rec.
                                             |   |__deadenylation-independent decapping of nuclear-transcribed mRNA(+) 6 rec.
                                             |__nuclear-transcribed mRNA catabolic process, no-go decay 1 rec.
                                             |__nuclear-transcribed mRNA catabolic process, non-stop decay 3 rec.
                                             |__nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 18 rec.
                                             |   |__nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay 2 rec.
                                             |   |__nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay
                                             |   |__regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(+) 1 rec.
                                             |__nuclear-transcribed mRNA catabolic process, RNase MRP-dependent
                                             |__nuclear-transcribed mRNA poly(A) tail shortening 17 rec.
                                                 |__regulation of nuclear-transcribed mRNA poly(A) tail shortening(+) 6 rec.
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Is a mRNA catabolic process
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Synonyms
  • "nuclear mRNA breakdown" EXACT
    "nuclear mRNA catabolism" EXACT
    "nuclear mRNA degradation" EXACT
Secondary IDs
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