FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term DNA-templated transcription open complex formation ID (Ontology) GO:0001112 (Gene Ontology)
Definition Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.[ PubMed:15020047 PubMed:18280161 ]
Also Known As "DNA-dependent transcriptional open complex formation" ; "DNA-templated transcriptional open complex formation"
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DNA-templated transcription
 |__DNA-templated transcription initiation__
RNA biosynthetic process                    |
 |__DNA-templated transcription initiation__|
protein-containing complex remodeling       |
 |__protein-DNA complex remodeling__________|
protein-DNA complex organization            |
 |__protein-DNA complex remodeling__________|
                                            DNA-templated transcription open complex formation  7 rec.
                                             |__transcription open complex formation at RNA polymerase II promoter 7 rec.
                                                 |__regulation of transcription open complex formation at RNA polymerase II promoter
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Is a protein-DNA complex remodeling
Part of DNA-templated transcription initiation
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Synonyms
  • "DNA-dependent transcriptional open complex formation" EXACT
    "DNA-templated transcriptional open complex formation" EXACT
    "promoter melting" BROAD
    "transcription open complex formation at bacterial-type RNA polymerase promoter" NARROW
    "transcriptional open complex formation at bacterial-type RNA polymerase promoter" NARROW
Secondary IDs
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