FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term ossification ID (Ontology) GO:0001503 (Gene Ontology)
Definition The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.[ PubMed:17572649 ]
Also Known As "bone biosynthesis" ; "bone formation" ; "osteogenesis"
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Spanning Tree (Parents/Children)
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  biological_process
   |__multicellular organismal process
       |__ossification
           |__bone mineralization
           |   |__bone mineralization involved in bone maturation(+)
           |   |__phosphatidylserine exposure on osteoblast involved in bone mineralization
           |   |__regulation of bone mineralization(+)
           |__direct ossification
           |   |__intramembranous ossification(+)
           |   |__metaplastic ossification
           |__intratendonous ossification
           |__ligamentous ossification
           |__ossification involved in bone maturation
           |   |__bone mineralization involved in bone maturation(+)
           |__ossification involved in bone remodeling
           |__osteoblast differentiation
           |   |__osteoblast development
           |   |__osteoblast fate commitment
           |   |__regulation of osteoblast differentiation(+)
           |__regulation of ossification
           |   |__negative regulation of ossification(+)
           |   |__positive regulation of ossification(+)
           |   |__regulation of bone mineralization(+)
           |__replacement ossification
               |__endochondral ossification
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Is a multicellular organismal process
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Synonyms
  • "bone biosynthesis" EXACT
    "bone formation" EXACT
    "osteogenesis" EXACT
Secondary IDs
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Wikipedia:Ossification