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| Term | peptide amidation | ID (Ontology) | GO:0001519 (Gene Ontology) |
| Definition | The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.[ PubMed:11028916 ] | ||
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peptide metabolic process |__peptide modification |__peptide amidation |
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| Is a | peptide modification | ||
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