FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term immunological synapse ID (Ontology) GO:0001772 (Gene Ontology)
Definition An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.[ PubMed:11244041 PubMed:11376300 ]
Also Known As "supramolecular activation cluster"
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  cellular_component
   |__cellular anatomical structure
       |__immunological synapse
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Is a cellular anatomical structure
Part of plasma membrane
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Wikipedia:Immunological_synapse