FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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General Information
Term regulation of cytokine production ID (Ontology) GO:0001817 (Gene Ontology)
Definition Any process that modulates the frequency, rate, or extent of production of a cytokine.[ ISBN:0781735149 ]
Also Known As "regulation of cytokine anabolism" ; "regulation of cytokine biosynthesis" ; "regulation of cytokine formation" (for all, see Synonyms field below)
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Spanning Tree (Parents/Children)
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gene expression
 |__cytokine production_____________________________
 |__regulation of gene expression___________________|
regulation of macromolecule biosynthetic process    |
 |__regulation of gene expression___________________|
multicellular organismal process                    |
 |__cytokine production_____________________________|
 |__regulation of multicellular organismal process__|
regulation of biological process                    |
 |__regulation of multicellular organismal process__|
                                                    regulation of cytokine production  5 rec.
                                                     |__negative regulation of cytokine production 2 rec.
                                                     |   |__negative regulation of chemokine production(+)
                                                     |   |__negative regulation of connective tissue growth factor production
                                                     |   |__negative regulation of cytokine production involved in immune response(+) 1 rec.
                                                     |   |__negative regulation of cytokine production involved in inflammatory response
                                                     |   |__negative regulation of endothelin production
                                                     |   |__negative regulation of fibroblast growth factor production
                                                     |   |__negative regulation of glial cell-derived neurotrophic factor production
                                                     |   |__negative regulation of granulocyte macrophage colony-stimulating factor production
                                                     |   |__negative regulation of hepatocyte growth factor production
                                                     |   |__negative regulation of interleukin-1 production(+)
                                                     |   |__negative regulation of interleukin-2 production
                                                     |   |__negative regulation of interleukin-3 production
                                                     |   |__negative regulation of interleukin-4 production
                                                     |   |__negative regulation of interleukin-5 production
                                                     |   |__negative regulation of interleukin-6 production
                                                     |   |__negative regulation of interleukin-7 production
                                                     |   |__negative regulation of interleukin-8 production
                                                     |   |__negative regulation of interleukin-9 production
                                                     |   |__negative regulation of interleukin-10 production
                                                     |   |__negative regulation of interleukin-11 production
                                                     |   |__negative regulation of interleukin-12 production
                                                     |   |__negative regulation of interleukin-13 production
                                                     |   |__negative regulation of interleukin-15 production
                                                     |   |__negative regulation of interleukin-16 production
                                                     |   |__negative regulation of interleukin-17 production(+)
                                                     |   |__negative regulation of interleukin-18 production
                                                     |   |__negative regulation of interleukin-19 production
                                                     |   |__negative regulation of interleukin-20 production
                                                     |   |__negative regulation of interleukin-21 production
                                                     |   |__negative regulation of interleukin-22 production
                                                     |   |__negative regulation of interleukin-23 production
                                                     |   |__negative regulation of interleukin-24 production
                                                     |   |__negative regulation of interleukin-25 production
                                                     |   |__negative regulation of interleukin-26 production
                                                     |   |__negative regulation of interleukin-27 production
                                                     |   |__negative regulation of interleukin-32 production
                                                     |   |__negative regulation of interleukin-33 production
                                                     |   |__negative regulation of interleukin-34 production
                                                     |   |__negative regulation of interleukin-35 production
                                                     |   |__negative regulation of interleukin-37 production
                                                     |   |__negative regulation of macrophage colony-stimulating factor production(+)
                                                     |   |__negative regulation of transforming growth factor beta production(+)
                                                     |   |__negative regulation of tumor necrosis factor superfamily cytokine production(+)
                                                     |   |__negative regulation of type I interferon production(+)
                                                     |   |__negative regulation of type II interferon production
                                                     |   |__negative regulation of type III interferon production
                                                     |   |__negative regulation of vascular endothelial growth factor production
                                                     |__positive regulation of cytokine production 3 rec.
                                                     |   |__positive regulation of amphiregulin production
                                                     |   |__positive regulation of chemokine production(+)
                                                     |   |__positive regulation of connective tissue growth factor production
                                                     |   |__positive regulation of cytokine production involved in immune response(+)
                                                     |   |__positive regulation of cytokine production involved in inflammatory response
                                                     |   |__positive regulation of endothelin production
                                                     |   |__positive regulation of fibroblast growth factor production
                                                     |   |__positive regulation of glial cell-derived neurotrophic factor production
                                                     |   |__positive regulation of granulocyte macrophage colony-stimulating factor production
                                                     |   |__positive regulation of hepatocyte growth factor production
                                                     |   |__positive regulation of interleukin-1 production(+)
                                                     |   |__positive regulation of interleukin-2 production
                                                     |   |__positive regulation of interleukin-3 production
                                                     |   |__positive regulation of interleukin-4 production
                                                     |   |__positive regulation of interleukin-5 production
                                                     |   |__positive regulation of interleukin-6 production
                                                     |   |__positive regulation of interleukin-7 production
                                                     |   |__positive regulation of interleukin-8 production
                                                     |   |__positive regulation of interleukin-9 production
                                                     |   |__positive regulation of interleukin-10 production
                                                     |   |__positive regulation of interleukin-11 production
                                                     |   |__positive regulation of interleukin-12 production
                                                     |   |__positive regulation of interleukin-13 production
                                                     |   |__positive regulation of interleukin-15 production
                                                     |   |__positive regulation of interleukin-16 production
                                                     |   |__positive regulation of interleukin-17 production(+)
                                                     |   |__positive regulation of interleukin-18 production
                                                     |   |__positive regulation of interleukin-19 production
                                                     |   |__positive regulation of interleukin-20 production
                                                     |   |__positive regulation of interleukin-21 production
                                                     |   |__positive regulation of interleukin-22 production
                                                     |   |__positive regulation of interleukin-23 production
                                                     |   |__positive regulation of interleukin-24 production
                                                     |   |__positive regulation of interleukin-25 production
                                                     |   |__positive regulation of interleukin-26 production
                                                     |   |__positive regulation of interleukin-27 production
                                                     |   |__positive regulation of interleukin-32 production
                                                     |   |__positive regulation of interleukin-33 production
                                                     |   |__positive regulation of interleukin-34 production
                                                     |   |__positive regulation of interleukin-35 production
                                                     |   |__positive regulation of interleukin-37 production
                                                     |   |__positive regulation of macrophage colony-stimulating factor production(+)
                                                     |   |__positive regulation of platelet-derived growth factor production
                                                     |   |__positive regulation of transforming growth factor beta production(+)
                                                     |   |__positive regulation of tumor necrosis factor superfamily cytokine production(+)
                                                     |   |__positive regulation of type I interferon production(+) 2 rec.
                                                     |   |__positive regulation of type II interferon production
                                                     |   |__positive regulation of type III interferon production
                                                     |   |__positive regulation of vascular endothelial growth factor production 1 rec.
                                                     |__regulation of amphiregulin production
                                                     |   |__positive regulation of amphiregulin production
                                                     |__regulation of chemokine production
                                                     |   |__negative regulation of chemokine production(+)
                                                     |   |__positive regulation of chemokine production(+)
                                                     |   |__regulation of chemokine (C-C motif) ligand 1 production(+)
                                                     |   |__regulation of chemokine (C-C motif) ligand 4 production(+)
                                                     |   |__regulation of chemokine (C-C motif) ligand 5 production(+)
                                                     |   |__regulation of chemokine (C-C motif) ligand 6 production(+)
                                                     |   |__regulation of chemokine (C-C motif) ligand 20 production(+)
                                                     |   |__regulation of chemokine (C-X-C motif) ligand 1 production(+)
                                                     |   |__regulation of chemokine (C-X-C motif) ligand 2 production(+)
                                                     |   |__regulation of chemokine (C-X-C motif) ligand 9 production(+)
                                                     |   |__regulation of fractalkine production(+)
                                                     |   |__regulation of IP-10 production(+)
                                                     |   |__regulation of macrophage inflammatory protein 1 alpha production(+)
                                                     |   |__regulation of macrophage inflammatory protein-1 gamma production(+)
                                                     |   |__regulation of monocyte chemotactic protein-1 production(+)
                                                     |__regulation of connective tissue growth factor production
                                                     |   |__negative regulation of connective tissue growth factor production
                                                     |   |__positive regulation of connective tissue growth factor production
                                                     |__regulation of cytokine production involved in immune response 1 rec.
                                                     |   |__negative regulation of cytokine production involved in immune response(+) 1 rec.
                                                     |   |__positive regulation of cytokine production involved in immune response(+)
                                                     |   |__regulation of B cell cytokine production(+)
                                                     |   |__regulation of dendritic cell cytokine production(+)
                                                     |   |__regulation of macrophage cytokine production(+) 1 rec.
                                                     |   |__regulation of mast cell cytokine production(+)
                                                     |   |__regulation of natural killer cell cytokine production(+)
                                                     |   |__regulation of T cell cytokine production(+)
                                                     |__regulation of cytokine production involved in inflammatory response
                                                     |   |__negative regulation of cytokine production involved in inflammatory response
                                                     |   |__positive regulation of cytokine production involved in inflammatory response
                                                     |__regulation of endothelin production
                                                     |   |__negative regulation of endothelin production
                                                     |   |__positive regulation of endothelin production
                                                     |__regulation of fibroblast growth factor production
                                                     |   |__negative regulation of fibroblast growth factor production
                                                     |   |__positive regulation of fibroblast growth factor production
                                                     |__regulation of glial cell-derived neurotrophic factor production
                                                     |   |__negative regulation of glial cell-derived neurotrophic factor production
                                                     |   |__positive regulation of glial cell-derived neurotrophic factor production
                                                     |__regulation of granulocyte macrophage colony-stimulating factor production
                                                     |   |__negative regulation of granulocyte macrophage colony-stimulating factor production
                                                     |   |__positive regulation of granulocyte macrophage colony-stimulating factor production
                                                     |__regulation of granzyme B production
                                                     |   |__negative regulation of granzyme B production
                                                     |   |__positive regulation of granzyme B production
                                                     |__regulation of hepatocyte growth factor production
                                                     |   |__negative regulation of hepatocyte growth factor production
                                                     |   |__positive regulation of hepatocyte growth factor production
                                                     |__regulation of interleukin-1 production
                                                     |   |__negative regulation of interleukin-1 production(+)
                                                     |   |__positive regulation of interleukin-1 production(+)
                                                     |   |__regulation of interleukin-1 alpha production(+)
                                                     |   |__regulation of interleukin-1 beta production(+)
                                                     |__regulation of interleukin-2 production
                                                     |   |__negative regulation of interleukin-2 production
                                                     |   |__positive regulation of interleukin-2 production
                                                     |__regulation of interleukin-3 production
                                                     |   |__negative regulation of interleukin-3 production
                                                     |   |__positive regulation of interleukin-3 production
                                                     |__regulation of interleukin-4 production
                                                     |   |__negative regulation of interleukin-4 production
                                                     |   |__positive regulation of interleukin-4 production
                                                     |__regulation of interleukin-5 production
                                                     |   |__negative regulation of interleukin-5 production
                                                     |   |__positive regulation of interleukin-5 production
                                                     |__regulation of interleukin-6 production
                                                     |   |__negative regulation of interleukin-6 production
                                                     |   |__positive regulation of interleukin-6 production
                                                     |__regulation of interleukin-7 production
                                                     |   |__negative regulation of interleukin-7 production
                                                     |   |__positive regulation of interleukin-7 production
                                                     |__regulation of interleukin-8 production
                                                     |   |__negative regulation of interleukin-8 production
                                                     |   |__positive regulation of interleukin-8 production
                                                     |__regulation of interleukin-9 production
                                                     |   |__negative regulation of interleukin-9 production
                                                     |   |__positive regulation of interleukin-9 production
                                                     |__regulation of interleukin-10 production
                                                     |   |__negative regulation of interleukin-10 production
                                                     |   |__positive regulation of interleukin-10 production
                                                     |__regulation of interleukin-11 production
                                                     |   |__negative regulation of interleukin-11 production
                                                     |   |__positive regulation of interleukin-11 production
                                                     |__regulation of interleukin-12 production
                                                     |   |__negative regulation of interleukin-12 production
                                                     |   |__positive regulation of interleukin-12 production
                                                     |__regulation of interleukin-13 production
                                                     |   |__negative regulation of interleukin-13 production
                                                     |   |__positive regulation of interleukin-13 production
                                                     |__regulation of interleukin-15 production
                                                     |   |__negative regulation of interleukin-15 production
                                                     |   |__positive regulation of interleukin-15 production
                                                     |__regulation of interleukin-16 production
                                                     |   |__negative regulation of interleukin-16 production
                                                     |   |__positive regulation of interleukin-16 production
                                                     |__regulation of interleukin-17 production
                                                     |   |__negative regulation of interleukin-17 production(+)
                                                     |   |__positive regulation of interleukin-17 production(+)
                                                     |   |__regulation of interleukin-17A production(+)
                                                     |__regulation of interleukin-18 production
                                                     |   |__negative regulation of interleukin-18 production
                                                     |   |__positive regulation of interleukin-18 production
                                                     |__regulation of interleukin-19 production
                                                     |   |__negative regulation of interleukin-19 production
                                                     |   |__positive regulation of interleukin-19 production
                                                     |__regulation of interleukin-20 production
                                                     |   |__negative regulation of interleukin-20 production
                                                     |   |__positive regulation of interleukin-20 production
                                                     |__regulation of interleukin-21 production
                                                     |   |__negative regulation of interleukin-21 production
                                                     |   |__positive regulation of interleukin-21 production
                                                     |__regulation of interleukin-22 production
                                                     |   |__negative regulation of interleukin-22 production
                                                     |   |__positive regulation of interleukin-22 production
                                                     |__regulation of interleukin-23 production
                                                     |   |__negative regulation of interleukin-23 production
                                                     |   |__positive regulation of interleukin-23 production
                                                     |__regulation of interleukin-24 production
                                                     |   |__negative regulation of interleukin-24 production
                                                     |   |__positive regulation of interleukin-24 production
                                                     |__regulation of interleukin-25 production
                                                     |   |__negative regulation of interleukin-25 production
                                                     |   |__positive regulation of interleukin-25 production
                                                     |__regulation of interleukin-26 production
                                                     |   |__negative regulation of interleukin-26 production
                                                     |   |__positive regulation of interleukin-26 production
                                                     |__regulation of interleukin-27 production
                                                     |   |__negative regulation of interleukin-27 production
                                                     |   |__positive regulation of interleukin-27 production
                                                     |__regulation of interleukin-32 production
                                                     |   |__negative regulation of interleukin-32 production
                                                     |   |__positive regulation of interleukin-32 production
                                                     |__regulation of interleukin-33 production
                                                     |   |__negative regulation of interleukin-33 production
                                                     |   |__positive regulation of interleukin-33 production
                                                     |__regulation of interleukin-34 production
                                                     |   |__negative regulation of interleukin-34 production
                                                     |   |__positive regulation of interleukin-34 production
                                                     |__regulation of interleukin-35 production
                                                     |   |__negative regulation of interleukin-35 production
                                                     |   |__positive regulation of interleukin-35 production
                                                     |__regulation of interleukin-37 production
                                                     |   |__negative regulation of interleukin-37 production
                                                     |   |__positive regulation of interleukin-37 production
                                                     |__regulation of macrophage colony-stimulating factor production
                                                     |   |__negative regulation of macrophage colony-stimulating factor production(+)
                                                     |   |__positive regulation of macrophage colony-stimulating factor production(+)
                                                     |   |__regulation of granulocyte colony-stimulating factor production(+)
                                                     |__regulation of platelet-derived growth factor production
                                                     |   |__positive regulation of platelet-derived growth factor production
                                                     |__regulation of transforming growth factor beta production
                                                     |   |__negative regulation of transforming growth factor beta production(+)
                                                     |   |__positive regulation of transforming growth factor beta production(+)
                                                     |   |__regulation of transforming growth factor beta1 production(+)
                                                     |   |__regulation of transforming growth factor beta2 production(+)
                                                     |   |__regulation of transforming growth factor beta3 production(+)
                                                     |__regulation of tumor necrosis factor superfamily cytokine production
                                                     |   |__negative regulation of tumor necrosis factor superfamily cytokine production(+)
                                                     |   |__positive regulation of tumor necrosis factor superfamily cytokine production(+)
                                                     |   |__regulation of lymphotoxin A production(+)
                                                     |   |__regulation of TRAIL production(+)
                                                     |   |__regulation of tumor necrosis factor (ligand) superfamily member 11 production(+)
                                                     |   |__regulation of tumor necrosis factor production(+)
                                                     |__regulation of type I interferon production 2 rec.
                                                     |   |__negative regulation of type I interferon production(+)
                                                     |   |__positive regulation of type I interferon production(+) 2 rec.
                                                     |   |__regulation of interferon-alpha production(+)
                                                     |   |__regulation of interferon-beta production(+)
                                                     |__regulation of type II interferon production
                                                     |   |__negative regulation of type II interferon production
                                                     |   |__positive regulation of type II interferon production
                                                     |__regulation of type III interferon production
                                                     |   |__negative regulation of type III interferon production
                                                     |   |__positive regulation of type III interferon production
                                                     |__regulation of vascular endothelial growth factor production 1 rec.
                                                         |__negative regulation of vascular endothelial growth factor production
                                                         |__positive regulation of vascular endothelial growth factor production 1 rec.
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Is a regulation of gene expression
regulation of multicellular organismal process
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Synonyms
  • "regulation of cytokine anabolism" EXACT
    "regulation of cytokine biosynthesis" EXACT
    "regulation of cytokine biosynthetic process" NARROW
    "regulation of cytokine formation" EXACT
    "regulation of cytokine secretion" NARROW
    "regulation of cytokine synthesis" EXACT
Secondary IDs
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