FB2025_05 , released December 11, 2025

CV Term Report

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General Information
Term	release of cytochrome c from mitochondria	ID (Ontology)	GO:0001836 (Gene Ontology)
Definition	The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.[ ISBN:0721639976 PubMed:12925707 PubMed:9560217 ]
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Spanning Tree (Parents/Children)

apoptotic process
 |__apoptotic mitochondrial changes__
 |__apoptotic signaling pathway______|
mitochondrion organization           |
 |__apoptotic mitochondrial changes__|
signal transduction                  |
 |__apoptotic signaling pathway______|
                                     release of cytochrome c from mitochondria  4 rec.
                                      |__regulation of release of cytochrome c from mitochondria 4 rec.
                                          |__negative regulation of release of cytochrome c from mitochondria 2 rec.
                                          |__positive regulation of release of cytochrome c from mitochondria 2 rec.

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Relationships
Is a	apoptotic mitochondrial changes
Part of	apoptotic signaling pathway
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