FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term regulation of cytokine-mediated signaling pathway ID (Ontology) GO:0001959 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.
Also Known As "regulation of cytokine and chemokine mediated signaling pathway" ; "regulation of cytokine mediated signaling pathway" ; "regulation of cytokine mediated signalling pathway"
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regulation of cell communication
 |__regulation of signal transduction____________
regulation of signaling                          |
 |__regulation of signal transduction____________|
regulation of response to stimulus               |
 |__regulation of signal transduction____________|
 |__regulation of response to cytokine stimulus__|
                                                 regulation of cytokine-mediated signaling pathway  14 rec.
                                                  |__negative regulation of cytokine-mediated signaling pathway 6 rec.
                                                  |   |__negative regulation of chemokine-mediated signaling pathway(+)
                                                  |   |__negative regulation of interleukin-1-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-2-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-4-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-6-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-17-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-18-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-27-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-35-mediated signaling pathway
                                                  |   |__negative regulation of Kit signaling pathway
                                                  |   |__negative regulation of macrophage colony-stimulating factor signaling pathway
                                                  |   |__negative regulation of macrophage migration inhibitory factor signaling pathway
                                                  |   |__negative regulation of prolactin signaling pathway
                                                  |   |__negative regulation of tumor necrosis factor-mediated signaling pathway 6 rec.
                                                  |   |__negative regulation of type I interferon-mediated signaling pathway
                                                  |   |__negative regulation of type II interferon-mediated signaling pathway
                                                  |__positive regulation of cytokine-mediated signaling pathway 8 rec.
                                                  |   |__positive regulation of chemokine-mediated signaling pathway(+)
                                                  |   |__positive regulation of interleukin-1-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-2-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-4-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-6-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-17-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-18-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-27-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-35-mediated signaling pathway
                                                  |   |__positive regulation of Kit signaling pathway
                                                  |   |__positive regulation of macrophage colony-stimulating factor signaling pathway
                                                  |   |__positive regulation of macrophage migration inhibitory factor signaling pathway
                                                  |   |__positive regulation of prolactin signaling pathway
                                                  |   |__positive regulation of tumor necrosis factor-mediated signaling pathway 8 rec.
                                                  |   |__positive regulation of type I interferon-mediated signaling pathway
                                                  |   |__positive regulation of type II interferon-mediated signaling pathway
                                                  |__regulation of chemokine-mediated signaling pathway
                                                  |   |__negative regulation of chemokine-mediated signaling pathway(+)
                                                  |   |__positive regulation of chemokine-mediated signaling pathway(+)
                                                  |   |__regulation of C-C chemokine receptor CCR7 signaling pathway(+)
                                                  |__regulation of interleukin-1-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-1-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-1-mediated signaling pathway
                                                  |__regulation of interleukin-2-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-2-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-2-mediated signaling pathway
                                                  |__regulation of interleukin-4-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-4-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-4-mediated signaling pathway
                                                  |__regulation of interleukin-6-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-6-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-6-mediated signaling pathway
                                                  |__regulation of interleukin-17-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-17-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-17-mediated signaling pathway
                                                  |__regulation of interleukin-18-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-18-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-18-mediated signaling pathway
                                                  |__regulation of interleukin-27-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-27-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-27-mediated signaling pathway
                                                  |__regulation of interleukin-35-mediated signaling pathway
                                                  |   |__negative regulation of interleukin-35-mediated signaling pathway
                                                  |   |__positive regulation of interleukin-35-mediated signaling pathway
                                                  |__regulation of Kit signaling pathway
                                                  |   |__negative regulation of Kit signaling pathway
                                                  |   |__positive regulation of Kit signaling pathway
                                                  |__regulation of macrophage colony-stimulating factor signaling pathway
                                                  |   |__negative regulation of macrophage colony-stimulating factor signaling pathway
                                                  |   |__positive regulation of macrophage colony-stimulating factor signaling pathway
                                                  |__regulation of macrophage migration inhibitory factor signaling pathway
                                                  |   |__negative regulation of macrophage migration inhibitory factor signaling pathway
                                                  |   |__positive regulation of macrophage migration inhibitory factor signaling pathway
                                                  |__regulation of prolactin signaling pathway
                                                  |   |__negative regulation of prolactin signaling pathway
                                                  |   |__positive regulation of prolactin signaling pathway
                                                  |__regulation of tumor necrosis factor-mediated signaling pathway 14 rec.
                                                  |   |__negative regulation of tumor necrosis factor-mediated signaling pathway 6 rec.
                                                  |   |__positive regulation of tumor necrosis factor-mediated signaling pathway 8 rec.
                                                  |__regulation of type I interferon-mediated signaling pathway
                                                  |   |__negative regulation of type I interferon-mediated signaling pathway
                                                  |   |__positive regulation of type I interferon-mediated signaling pathway
                                                  |__regulation of type II interferon-mediated signaling pathway
                                                      |__negative regulation of type II interferon-mediated signaling pathway
                                                      |__positive regulation of type II interferon-mediated signaling pathway
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Is a regulation of signal transduction
regulation of response to cytokine stimulus
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Synonyms
  • "regulation of cytokine and chemokine mediated signaling pathway" EXACT
    "regulation of cytokine mediated signaling pathway" EXACT
    "regulation of cytokine mediated signalling pathway" EXACT
Secondary IDs
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Reactome:R-HSA-8939247 "RUNX1 regulates transcription of genes involved in interleukin signaling"