FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cap-independent translational initiation ID (Ontology) GO:0002190 (Gene Ontology)
Definition The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation.[ PubMed:17284590 ]
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cytoplasmic translation___
translational initiation__|
                          cytoplasmic translational initiation
                           |__cap-independent translational initiation  1 rec.
                               |__cap-independent translational initiation of circular RNA
                               |   |__IRES-dependent translational initiation of circular RNA
                               |__cap-independent translational initiation of linear mRNA 1 rec.
                               |   |__IRES-dependent translational initiation of linear mRNA 1 rec.
                               |__regulation of cap-independent translational initiation
                                   |__negative regulation of cap-independent translational initiation
                                   |__positive regulation of cap-independent translational initiation
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Is a cytoplasmic translational initiation
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