FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term somatic hypermutation of immunoglobulin genes involved in immune response ID (Ontology) GO:0002205 (Gene Ontology)
Definition Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response.[ ISBN:0781735149 PubMed:11205333 PubMed:14991701 ]
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peripheral B cell selection
 |__B cell affinity maturation_________________________________________________
immunoglobulin production involved in immunoglobulin-mediated immune response  |
 |__somatic diversification of immunoglobulins involved in immune response_____|
 |__B cell affinity maturation_________________________________________________|
somatic diversification of immune receptors via somatic mutation               |
 |__somatic hypermutation of immunoglobulin genes______________________________|
somatic diversification of immunoglobulins                                     |
 |__somatic diversification of immunoglobulins involved in immune response_____|
 |__somatic hypermutation of immunoglobulin genes______________________________|
                                                                               somatic hypermutation of immunoglobulin genes involved in immune response
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Is a somatic diversification of immunoglobulins involved in immune response
somatic hypermutation of immunoglobulin genes
Part of B cell affinity maturation
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Synonyms
  • "somatic hypermutation of antibody genes during immune response" RELATED
    "somatic hypermutation of immunoglobulin genes during immune response" RELATED
Secondary IDs
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