FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term pattern recognition receptor signaling pathway ID (Ontology) GO:0002221 (Gene Ontology)
Definition The series of molecular signals initiated by a ligand binding to a pattern recognition receptor (PRR), and ending with the regulation of a downstream cellular process, e.g. transcription. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.[ ISBN:0781735149 PubMed:15199967 ]
Also Known As "pathogen receptor signaling pathway" ; "pathogen receptor signalling pathway" ; "PRR signaling pathway"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 pattern recognition receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | pattern recognition receptor signaling pathway       3
Spanning Tree (Parents/Children)
Only view relationship:
activation of innate immune response__________
immune response-activating signaling pathway__|
                                              innate immune response-activating signaling pathway
                                               |__pattern recognition receptor signaling pathway  101 rec.
                                                   |__cell surface pattern recognition receptor signaling pathway 3 rec.
                                                   |   |__cell surface toll-like receptor signaling pathway(+) 2 rec.
                                                   |   |__toll-like receptor 1 signaling pathway(+)
                                                   |__cytoplasmic pattern recognition receptor signaling pathway 9 rec.
                                                   |   |__cGAS/STING signaling pathway 7 rec.
                                                   |   |__endolysosomal toll-like receptor signaling pathway(+)
                                                   |   |__endosomal pattern recognition receptor signaling pathway
                                                   |   |__inflammasome-mediated signaling pathway(+)
                                                   |   |__MDA-5 signaling pathway(+)
                                                   |   |__nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(+)
                                                   |   |__regulation of cytoplasmic pattern recognition receptor signaling pathway(+) 2 rec.
                                                   |   |__RIG-I signaling pathway(+)
                                                   |__pathogen-associated molecular pattern receptor signaling pathway
                                                   |__peptidoglycan recognition protein signaling pathway 88 rec.
                                                   |   |__regulation of peptidoglycan recognition protein signaling pathway(+) 67 rec.
                                                   |__regulation of pattern recognition receptor signaling pathway 69 rec.
                                                   |   |__positive regulation of pattern recognition receptor signaling pathway(+) 23 rec.
                                                   |   |__regulation of cytoplasmic pattern recognition receptor signaling pathway(+) 2 rec.
                                                   |   |__regulation of peptidoglycan recognition protein signaling pathway(+) 67 rec.
                                                   |   |__regulation of toll-like receptor 1 signaling pathway(+)
                                                   |   |__regulation of toll-like receptor 2 signaling pathway(+)
                                                   |   |__regulation of toll-like receptor 4 signaling pathway(+)
                                                   |   |__regulation of toll-like receptor 5 signaling pathway(+)
                                                   |   |__regulation of toll-like receptor 6 signaling pathway(+)
                                                   |   |__regulation of toll-like receptor 10 signaling pathway(+)
                                                   |   |__regulation of toll-like receptor 15 signaling pathway(+)
                                                   |   |__regulation of toll-like receptor signaling pathway(+)
                                                   |__toll-like receptor signaling pathway
                                                       |__MyD88-dependent toll-like receptor signaling pathway(+)
                                                       |__MyD88-independent toll-like receptor signaling pathway(+)
                                                       |__regulation of toll-like receptor signaling pathway(+)
                                                       |__TIRAP-dependent toll-like receptor signaling pathway(+)
                                                       |__toll-like receptor 21 signaling pathway(+)
                                                       |__toll-like receptor TLR1:TLR2 signaling pathway
                                                       |__toll-like receptor TLR6:TLR2 signaling pathway
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a innate immune response-activating signaling pathway
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts