FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term kinin cascade ID (Ontology) GO:0002254 (Gene Ontology)
Definition A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.[ ISBN:0721601871 PubMed:11842287 PubMed:14501145 ]
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inflammatory response
 |__acute inflammatory response__
protein maturation               |
 |__protein activation cascade___|
                                 kinin cascade
                                  |__plasma kallikrein-kinin cascade
                                  |   |__Factor XII activation
                                  |   |__regulation of plasma kallikrein-kinin cascade(+)
                                  |__regulation of kinin cascade
                                  |   |__negative regulation of kinin cascade(+)
                                  |   |__positive regulation of kinin cascade(+)
                                  |   |__regulation of plasma kallikrein-kinin cascade(+)
                                  |   |__regulation of tissue kallikrein-kinin cascade(+)
                                  |__tissue kallikrein-kinin cascade
                                      |__regulation of tissue kallikrein-kinin cascade(+)
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Is a acute inflammatory response
protein activation cascade
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