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| Term | tissue kallikrein-kinin cascade | ID (Ontology) | GO:0002255 (Gene Ontology) |
| Definition | A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.[ PubMed:11842287 PubMed:14501145 ] | ||
| Also Known As | "glandular kallikrein-kinin cascade" | ||
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acute inflammatory response__ protein activation cascade___| kinin cascade |__tissue kallikrein-kinin cascade |__regulation of tissue kallikrein-kinin cascade |__negative regulation of tissue kallikrein-kinin cascade |__positive regulation of tissue kallikrein-kinin cascade |
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| Is a | kinin cascade | ||
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