FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term T-helper 1 cell lineage commitment ID (Ontology) GO:0002296 (Gene Ontology)
Definition The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.[ ISBN:0781735149 ]
Also Known As "T-helper 1 cell fate commitment" ; "Th1 cell lineage commitment" ; "Th1 fate commitment"
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T-helper 1 type immune response
 |__T-helper 1 cell differentiation_________________
T-helper cell differentiation                       |
 |__T-helper cell lineage commitment________________|
 |__T-helper 1 cell differentiation_________________|
CD4-positive, alpha-beta T cell lineage commitment  |
 |__T-helper cell lineage commitment________________|
                                                    T-helper 1 cell lineage commitment
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Is a T-helper cell lineage commitment
Part of T-helper 1 cell differentiation
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Synonyms
  • "T-helper 1 cell fate commitment" EXACT[ ISBN:0781735149 ]
    "Th1 cell lineage commitment" EXACT[ ISBN:0781735149 ]
    "Th1 fate commitment" EXACT[ ISBN:0781735149 ]
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