FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term germinal center B cell differentiation ID (Ontology) GO:0002314 (Gene Ontology)
Definition The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).[ ISBN:0781735149 ]
Also Known As "germinal center B lymphocyte differentiation" ; "germinal center B-cell differentiation" ; "germinal center B-lymphocyte differentiation"
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B cell activation involved in immune response__
mature B cell differentiation__________________|
                                               mature B cell differentiation involved in immune response
                                                |__germinal center B cell differentiation
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Is a mature B cell differentiation involved in immune response
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Synonyms
  • "germinal center B cell development" RELATED
    "germinal center B lymphocyte differentiation" EXACT
    "germinal center B-cell differentiation" EXACT
    "germinal center B-lymphocyte differentiation" EXACT
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