FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term pre-B cell receptor expression ID (Ontology) GO:0002330 (Gene Ontology)
Definition The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.[ PubMed:15263090 PubMed:22949502 PubMed:9834086 ]
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immature B cell differentiation
 |__pre-B cell differentiation______
cellular process                    |
 |__cellular developmental process__|
developmental process               |
 |__cellular developmental process__|
                                    pre-B cell receptor expression
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Is a cellular developmental process
Part of pre-B cell differentiation
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