FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term immune system process ID (Ontology) GO:0002376 (Gene Ontology)
Definition Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
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  QuickGO data     AmiGO data
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Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       8
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
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 Genes
 immune system process (all annotations which use CV term, excluding "NOT" statements)       8
     involved_in | immune system process       8
Spanning Tree (Parents/Children)
Only view relationship:
  biological_process
   |__immune system process  614 rec.
       |__activation of immune response 104 rec.
       |   |__activation of innate immune response(+) 103 rec.
       |   |__complement activation(+)
       |   |__immune response-activating signaling pathway(+) 101 rec.
       |__antigen processing and presentation 1 rec.
       |   |__antigen processing and presentation following phagocytosis
       |   |__antigen processing and presentation following pinocytosis(+)
       |   |__antigen processing and presentation initiated by receptor mediated uptake of antigen(+)
       |   |__antigen processing and presentation of endogenous antigen(+)
       |   |__antigen processing and presentation of exogenous antigen(+)
       |   |__antigen processing and presentation of peptide antigen(+) 1 rec.
       |   |__antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(+) 1 rec.
       |   |__antigen processing and presentation via MHC class Ib(+)
       |   |__B cell antigen processing and presentation(+)
       |   |__dendritic cell antigen processing and presentation(+)
       |   |__macrophage antigen processing and presentation
       |   |__monocyte antigen processing and presentation
       |   |__non-professional antigen presenting cell antigen processing and presentation
       |   |__T cell antigen processing and presentation
       |__antigen sampling in mucosal-associated lymphoid tissue
       |   |__antigen sampling by dendritic cells in mucosal-associated lymphoid tissue
       |   |__antigen sampling by M cells in mucosal-associated lymphoid tissue
       |__B cell selection
       |   |__B cell negative selection(+)
       |   |__B cell positive selection(+)
       |   |__central B cell selection(+)
       |   |__peripheral B cell selection(+)
       |__hemocyte differentiation 51 rec.
       |   |__crystal cell differentiation(+) 25 rec.
       |   |__embryonic hemocyte differentiation(+) 3 rec.
       |   |__larval lymph gland hemocyte differentiation(+) 30 rec.
       |   |__plasmatocyte differentiation(+) 13 rec.
       |__hemocyte proliferation 46 rec.
       |__immune effector process 124 rec.
       |   |__cell activation involved in immune response(+)
       |   |__complement activation(+)
       |   |__encapsulation of foreign target(+) 41 rec.
       |   |__granuloma formation
       |   |__immune complex clearance(+)
       |   |__immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(+)
       |   |__induced systemic resistance, ethylene mediated signaling pathway
       |   |__induced systemic resistance, jasmonic acid mediated signaling pathway
       |   |__leukocyte degranulation(+)
       |   |__leukocyte mediated immunity(+)
       |   |__leukocyte migration involved in immune response(+)
       |   |__opsonization 1 rec.
       |   |__respiratory burst involved in defense response(+)
       |__immune response 516 rec.
       |   |__adaptive immune response(+)
       |   |__humoral immune response(+) 151 rec.
       |   |__immune response in gut-associated lymphoid tissue(+)
       |   |__immune response involved in response to exogenous dsRNA 3 rec.
       |   |__immune response to tumor cell(+)
       |   |__inflammatory response to antigenic stimulus(+)
       |   |__innate immune response(+) 368 rec.
       |   |__organ or tissue specific immune response(+) 12 rec.
       |   |__type 2 immune response
       |__immune system development 53 rec.
       |__immunological memory process
       |   |__adaptive immune memory response(+)
       |   |__immunological memory formation process(+)
       |   |__innate immunity memory response
       |__leukocyte activation 2 rec.
       |   |__leukocyte activation involved in immune response(+)
       |   |__leukocyte activation involved in inflammatory response(+)
       |   |__leukocyte adhesive activation
       |   |__lymphocyte activation(+)
       |   |__myeloid leukocyte activation(+)
       |   |__plasmacytoid dendritic cell activation(+)
       |__leukocyte homeostasis
       |   |__basophil homeostasis
       |   |__dendritic cell homeostasis
       |   |__eosinophil homeostasis
       |   |__lymphocyte homeostasis(+)
       |   |__macrophage homeostasis
       |   |__mast cell homeostasis
       |   |__monocyte homeostasis
       |   |__neutrophil homeostasis
       |__leukocyte migration
       |   |__cellular extravasation(+)
       |   |__diapedesis(+)
       |   |__leukocyte chemotaxis(+)
       |   |__leukocyte migration involved in immune response(+)
       |   |__leukocyte migration involved in inflammatory response(+)
       |   |__mononuclear cell migration(+)
       |   |__myeloid leukocyte migration(+)
       |__lymphocyte costimulation
       |   |__B cell costimulation
       |   |__T cell costimulation(+)
       |__myeloid cell homeostasis
       |   |__basophil homeostasis
       |   |__eosinophil homeostasis
       |   |__erythrocyte homeostasis
       |   |__macrophage homeostasis
       |   |__mast cell homeostasis
       |   |__monocyte homeostasis
       |   |__neutrophil homeostasis
       |__production of molecular mediator of immune response 86 rec.
       |   |__antimicrobial peptide production(+) 85 rec.
       |   |__cytokine production involved in immune response(+) 1 rec.
       |   |__granulysin production
       |   |__granzyme A production
       |   |__granzyme B production
       |   |__immunoglobulin production(+)
       |   |__perforin production
       |__somatic diversification of immune receptors
       |   |__somatic diversification of DSCAM-based immune receptors
       |   |__somatic diversification of FREP-based immune receptors
       |   |__somatic diversification of immune receptors by N region addition(+)
       |   |__somatic diversification of immune receptors via alternate splicing(+)
       |   |__somatic diversification of immune receptors via gene conversion(+)
       |   |__somatic diversification of immune receptors via germline recombination within a single locus(+)
       |   |__somatic diversification of immune receptors via somatic mutation(+)
       |   |__somatic diversification of immunoglobulins(+)
       |   |__somatic diversification of T cell receptor genes(+)
       |   |__somatic diversification of variable lymphocyte receptors of jawless fish
       |__T cell selection
       |   |__beta selection
       |   |__extrathymic T cell selection(+)
       |   |__negative T cell selection(+)
       |   |__positive T cell selection(+)
       |   |__thymic T cell selection(+)
       |__tolerance induction
           |__B cell tolerance induction(+)
           |__central tolerance induction(+)
           |__lymphocyte anergy(+)
           |__macrophage tolerance induction
           |__natural killer cell tolerance induction
           |__T cell tolerance induction(+)
           |__tolerance induction dependent upon immune response(+)
           |__tolerance induction to lipopolysaccharide
           |__tolerance induction to self antigen(+)
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Wikipedia:Immune_system