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General Information
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| Term |
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor |
ID (Ontology) |
GO:0002415 (Gene Ontology) |
| Definition |
The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa.[ ISBN:0781735149 PubMed:16048543 ] |
| Also Known As |
"antibody transcytosis mediated by pIgR" ; "immunoglobulin transcytosis mediated by pIgR" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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No relevant statements available
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Relationships
