FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term granuloma formation ID (Ontology) GO:0002432 (Gene Ontology)
Definition The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.[ ISBN:0721601464 ]
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immune system process
 |__immune effector process________
inflammatory response              |
 |__chronic inflammatory response__|
                                   granuloma formation
                                    |__regulation of granuloma formation
                                        |__negative regulation of granuloma formation
                                        |__positive regulation of granuloma formation
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Is a immune effector process
Part of chronic inflammatory response
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