General Information
Term	immune system development	ID (Ontology)	GO:0002520 (Gene Ontology)
Definition	The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
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General Information

Term

immune system development

ID (Ontology)

GO:0002520 (Gene Ontology)

Definition

The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

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QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

multicellular organism development
 |__system development____________
biological_process                |
 |__immune system process_________|
anatomical structure development  |
 |__system development____________|
                                  immune system development  53 rec.
                                   |__hematopoietic or lymphoid organ development 53 rec.
                                   |   |__bone marrow development
                                   |   |__bursa of Fabricius development
                                   |   |__head kidney development(+)
                                   |   |__lymph gland development(+) 53 rec.
                                   |   |__lymph node development
                                   |   |__mucosa-associated lymphoid tissue development(+)
                                   |   |__spleen development(+)
                                   |   |__thymus development(+)
                                   |__somatic diversification of immune receptors
                                   |   |__somatic diversification of DSCAM-based immune receptors
                                   |   |__somatic diversification of FREP-based immune receptors
                                   |   |__somatic diversification of immune receptors by N region addition(+)
                                   |   |__somatic diversification of immune receptors via alternate splicing(+)
                                   |   |__somatic diversification of immune receptors via gene conversion(+)
                                   |   |__somatic diversification of immune receptors via germline recombination within a single locus(+)
                                   |   |__somatic diversification of immune receptors via somatic mutation(+)
                                   |   |__somatic diversification of immunoglobulins(+)
                                   |   |__somatic diversification of T cell receptor genes(+)
                                   |   |__somatic diversification of variable lymphocyte receptors of jawless fish
                                   |__tolerance induction
                                       |__B cell tolerance induction(+)
                                       |__central tolerance induction(+)
                                       |__lymphocyte anergy(+)
                                       |__macrophage tolerance induction(+)
                                       |__natural killer cell tolerance induction(+)
                                       |__regulation of tolerance induction(+)
                                       |__T cell tolerance induction(+)
                                       |__tolerance induction dependent upon immune response(+)
                                       |__tolerance induction to lipopolysaccharide
                                       |__tolerance induction to self antigen(+)

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system development

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