FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term innate immune response-activating signaling pathway ID (Ontology) GO:0002758 (Gene Ontology)
Definition The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an innate immune response.[ PubMed:11418339 PubMed:28105028 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       3
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 innate immune response-activating signaling pathway (all annotations which use CV term, excluding "NOT" statements)       3
     involved_in | innate immune response-activating signaling pathway       3
Spanning Tree (Parents/Children)
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activation of immune response
 |__activation of innate immune response__________
 |__immune response-activating signaling pathway__|
immune response-regulating signaling pathway      |
 |__immune response-activating signaling pathway__|
positive regulation of innate immune response     |
 |__activation of innate immune response__________|
                                                  innate immune response-activating signaling pathway  101 rec.
                                                   |__innate immune response activating cell surface receptor signaling pathway 3 rec.
                                                   |   |__cell surface pattern recognition receptor signaling pathway(+) 3 rec.
                                                   |   |__stimulatory C-type lectin receptor signaling pathway
                                                   |   |__stimulatory killer cell immunoglobulin-like receptor signaling pathway
                                                   |__pattern recognition receptor signaling pathway 101 rec.
                                                       |__cell surface pattern recognition receptor signaling pathway(+) 3 rec.
                                                       |__cytoplasmic pattern recognition receptor signaling pathway(+) 9 rec.
                                                       |__pathogen-associated molecular pattern receptor signaling pathway
                                                       |__peptidoglycan recognition protein signaling pathway(+) 88 rec.
                                                       |__regulation of pattern recognition receptor signaling pathway(+) 69 rec.
                                                       |__toll-like receptor signaling pathway(+)
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Is a activation of innate immune response
immune response-activating signaling pathway
Part of
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Synonyms
  • "defence response signaling pathway, resistance gene-dependent" RELATED
    "defence response signaling pathway, resistance gene-independent" RELATED
    "defence response signalling pathway, resistance gene-dependent" RELATED
    "defence response signalling pathway, resistance gene-independent" RELATED
    "defense response signaling pathway, resistance gene-dependent" RELATED
    "defense response signaling pathway, resistance gene-independent" RELATED
    "defense response signalling pathway, resistance gene-dependent" RELATED
    "effector triggered immunity" BROAD
    "effector-triggered immune signaling" RELATED
    "effector-triggered immunity" BROAD
Secondary IDs
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