FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term epithelial to mesenchymal transition involved in endocardial cushion formation ID (Ontology) GO:0003198 (Gene Ontology)
Definition A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.
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epithelial to mesenchymal transition
 |__cardiac epithelial to mesenchymal transition__________
heart morphogenesis                                       |
 |__cardiac epithelial to mesenchymal transition__________|
endocardial cushion morphogenesis                         |
 |__endocardial cushion formation_________________________|
anatomical structure formation involved in morphogenesis  |
 |__endocardial cushion formation_________________________|
                                                          epithelial to mesenchymal transition involved in endocardial cushion formation
                                                           |__regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
                                                               |__negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
                                                               |__positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
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Is a cardiac epithelial to mesenchymal transition
Part of endocardial cushion formation
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