FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term nuclear envelope ID (Ontology) GO:0005635 (Gene Ontology)
Definition The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport.[ ISBN:0198547684 PubMed:16164970 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       3
Genes (FBgn)  GO_CELLULAR_COMPONENT      68
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 nuclear envelope (all annotations which use CV term, excluding "NOT" statements)       4     71      2
     colocalizes_with | nuclear envelope       --      10       --
     is_active_in | nuclear envelope       --      17       --
     located_in | nuclear envelope       --      47       --
     nuclear envelope | adult stage       7       --       6
     nuclear envelope | embryonic stage 5       1       --       --
     nuclear envelope | germline clone | maternal effect | pre-blastoderm stage       1       --       --
     nuclear envelope | larval stage      20       --      15
     nuclear envelope | larval stage | male       1       --       --
     nuclear envelope | third instar larval stage       8       --       2
Spanning Tree (Parents/Children)
Only view relationship:
membrane-bounded organelle
 |__organelle envelope____________________
intracellular organelle                   |
 |__organelle envelope____________________|
intracellular membrane-bounded organelle  |
 |__nucleus_______________________________|
cellular anatomical structure             |
 |__endomembrane system___________________|
 |__organelle envelope____________________|
                                          nuclear envelope  159 rec.
                                           |__microtubule organizing center attachment site 3 rec.
                                           |   |__meiotic nuclear membrane microtubule tethering complex(+) 3 rec.
                                           |   |__mitotic spindle pole body attachment site
                                           |__nuclear envelope adjacent to nuclear pore complex
                                           |__nuclear envelope lumen 2 rec.
                                           |__nuclear lamina 16 rec.
                                           |   |__lamin filament 3 rec.
                                           |__nuclear membrane 49 rec.
                                           |   |__5-lipoxygenase complex
                                           |   |__nuclear inner membrane(+) 8 rec.
                                           |   |__nuclear outer membrane(+) 5 rec.
                                           |__nuclear membrane protein complex 5 rec.
                                           |   |__nuclear membrane microtubule tethering complex(+) 3 rec.
                                           |__nuclear pore 51 rec.
                                           |   |__cytoplasmic side of nuclear pore
                                           |   |__nuclear pore central transport channel 8 rec.
                                           |   |__nuclear pore cytoplasmic filaments 4 rec.
                                           |   |__nuclear pore inner ring 4 rec.
                                           |   |__nuclear pore linkers
                                           |   |__nuclear pore nuclear basket 4 rec.
                                           |   |__nuclear pore outer ring 8 rec.
                                           |   |__nuclear pore transmembrane ring 2 rec.
                                           |   |__nucleoplasmic side of nuclear pore
                                           |__nucleoplasmic reticulum
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Is a organelle envelope
Part of nucleus
endomembrane system
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Wikipedia:Nuclear_envelope