FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term nuclear lamina ID (Ontology) GO:0005652 (Gene Ontology)
Definition The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.[ ISBN:0198506732 ISBN:0716731363 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      15
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 nuclear lamina (all annotations which use CV term, excluding "NOT" statements)       --      15       --
     colocalizes_with | nuclear lamina       --       1       --
     is_active_in | nuclear lamina       --       3       --
     located_in | nuclear lamina       --      14       --
     nuclear lamina | adult stage | male       7       --       --
     nuclear lamina | larval stage       7       --       2
     nuclear lamina | third instar larval stage       6       --       2
Spanning Tree (Parents/Children)
Only view relationship:
cellular_component
 |__cellular anatomical structure__
nucleus                            |
 |__nuclear envelope_______________|
endomembrane system                |
 |__nuclear envelope_______________|
organelle envelope                 |
 |__nuclear envelope_______________|
nuclear lumen                      |
 |__nuclear periphery______________|
cellular anatomical structure      |
 |__nuclear periphery______________|
                                   nuclear lamina  16 rec.
                                    |__lamin filament 3 rec.
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Is a cellular anatomical structure
Part of nuclear envelope
nuclear periphery
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Synonyms
Secondary IDs
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NIF_Subcellular:sao1455996588
Wikipedia:Nuclear_lamina