FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term nuclear pre-replicative complex ID (Ontology) GO:0005656 (Gene Ontology)
Definition A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.[ PubMed:15222894 ]
Also Known As "eukaryotic pre-replicative complex"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 nuclear pre-replicative complex (all annotations which use CV term, excluding "NOT" statements)       2
     part_of | nuclear pre-replicative complex       2
Spanning Tree (Parents/Children)
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nucleus
 |__nuclear protein-containing complex__
nuclear lumen                           |
 |__nucleoplasm_________________________|
protein-containing complex              |
 |__nuclear protein-containing complex__|
protein-DNA complex                     |
 |__pre-replicative complex_____________|
cellular anatomical structure           |
 |__nucleoplasm_________________________|
                                        nuclear pre-replicative complex  2 rec.
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Is a pre-replicative complex
nuclear protein-containing complex
Part of nucleoplasm
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Synonyms
  • "eukaryotic pre-replicative complex" EXACT
    "pre-RC" RELATED
    "pre-replicative complex" BROAD
Secondary IDs
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