FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
Help Close All Open All
General Information
Term DNA replication factor A complex ID (Ontology) GO:0005662 (Gene Ontology)
Definition A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.[ PubMed:9242902 ]
Also Known As "replication protein A" ; "RPA"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 DNA replication factor A complex (all annotations which use CV term, excluding "NOT" statements)       3
     part_of | DNA replication factor A complex       3
Spanning Tree (Parents/Children)
Only view relationship: 
  protein-containing complex
   |__nuclear protein-containing complex
       |__DNA replication factor A complex  3 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a nuclear protein-containing complex
Part of nuclear replisome
hide Synonyms & Secondary IDs
Synonyms
  • "replication protein A" EXACT
    "RPA" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Wikipedia:Replication_protein_A