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General Information
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| Term |
anaphase-promoting complex |
ID (Ontology) |
GO:0005680 (Gene Ontology) |
| Definition |
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.[ PubMed:10465783 PubMed:10611969 ] |
| Also Known As |
"anaphase promoting complex" ; "cyclosome" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 18 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Gene Groups | Genes |
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anaphase-promoting complex (all annotations which use CV term, excluding "NOT" statements) | 1 | 18 | part_of | anaphase-promoting complex | -- | 18 |
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Relationships
