FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term RNA polymerase I complex ID (Ontology) GO:0005736 (Gene Ontology)
Definition RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
Also Known As "DNA-directed RNA polymerase I complex"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      13
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Relevant FlyBase reports
 Gene Groups Genes
 RNA polymerase I complex (all annotations which use CV term, excluding "NOT" statements)       1     13
     part_of | RNA polymerase I complex       --      13
Spanning Tree (Parents/Children)
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nucleus
 |__nuclear protein-containing complex___
RNA polymerase complex                   |
 |__DNA-directed RNA polymerase complex__|
nuclear lumen                            |
 |__nucleolus____________________________|
protein-containing complex               |
 |__nuclear protein-containing complex___|
intracellular membraneless organelle     |
 |__nucleolus____________________________|
                                         RNA polymerase I complex  14 rec.
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Is a DNA-directed RNA polymerase complex
nuclear protein-containing complex
Part of nucleolus
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Synonyms
  • "DNA-directed RNA polymerase I activity" RELATED
    "DNA-directed RNA polymerase I complex" EXACT
Secondary IDs
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