FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term lysosome ID (Ontology) GO:0005764 (Gene Ontology)
Definition A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.[ ISBN:0198506732 ]
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      33
Genes (FBgn)  GO_CELLULAR_COMPONENT      93
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      20
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Gene Groups Genes Constructs
 lysosome (all annotations which use CV term, excluding "NOT" statements)      34      6     93     20
     colocalizes_with | lysosome       --       --       2       --
     is_active_in | lysosome       --       --      60       --
     located_in | lysosome       --       --      43       --
     lysosome | adult stage      46       --       --      32
     lysosome | adult stage | decreased number       2       --       --       2
     lysosome | adult stage | heat sensitive       1       --       --       --
     lysosome | adult stage | increased number      16       --       --      12
     lysosome | adult stage | nutrition conditional      12       --       --      10
     lysosome | adult stage | progressive       6       --       --       2
     lysosome | adult stage | somatic clone       3       --       --       --
     lysosome | cell autonomous | increased number | larval stage | somatic clone - tissue specific       1       --       --       --
     lysosome | cell autonomous | somatic clone | third instar larval stage       7       --       --       6
     lysosome | conditional | somatic clone       3       --       --       2
     lysosome | decreased number | early third instar larval stage       1       --       --       --
     lysosome | decreased number | larval stage       2       --       --       2
     lysosome | decreased number | spermatogenesis       4       --       --       3
     lysosome | decreased number | third instar larval stage       1       --       --       --
     lysosome | early third instar larval stage       4       --       --       3
     lysosome | early third instar larval stage | nutrition conditional       2       --       --       2
     lysosome | germline clone | oogenesis       1       --       --       --
     lysosome | increased number       1       --       --       --
     lysosome | increased number | larval stage       4       --       --       4
     lysosome | increased number | spermatogenesis       2       --       --       1
     lysosome | increased number | third instar larval stage       3       --       --       4
     lysosome | larval stage      24       --       --       9
     lysosome | larval stage | increased number       1       --       --       --
     lysosome | larval stage | somatic clone       4       --       --       4
     lysosome | larval stage | somatic clone | calorie restriction conditional       3       --       --       3
     lysosome | nutrition conditional       3       --       --       3
     lysosome | oogenesis | somatic clone       1       --       --       --
     lysosome | progressive       5       --       --       4
     lysosome | pupal stage       2       --       --       --
     lysosome | second instar larval stage       1       --       --       --
     lysosome | second instar larval stage | somatic clone       2       --       --       --
     lysosome | somatic clone       2       --       --       --
     lysosome | somatic clone | calorie restriction conditional       1       --       --       --
     lysosome | somatic clone | third instar larval stage       6       --       --       3
     lysosome | somatic clone | third instar larval stage | calorie restriction conditional       1       --       --       --
     lysosome | third instar larval stage      28       --       --      19
     lysosome | third instar larval stage | nutrition conditional       1       --       --       --
Spanning Tree (Parents/Children)
Only view relationship:
  vacuole
   |__lytic vacuole
       |__lysosome  215 rec.
           |__cytolytic granule
           |   |__cytolytic granule lumen
           |   |__cytolytic granule membrane
           |__endolysosome 12 rec.
           |   |__endolysosome lumen
           |   |__endolysosome membrane 3 rec.
           |__lysosomal glycocalyx
           |__lysosomal lumen 2 rec.
           |   |__acrosomal lumen
           |   |__endolysosome lumen
           |   |__lysosomal matrix
           |__lysosomal membrane 36 rec.
           |   |__autolysosome membrane 2 rec.
           |   |__azurophil granule membrane
           |   |__chaperone-mediated autophagy translocation complex
           |   |__cytolytic granule membrane
           |   |__cytoplasmic side of lysosomal membrane 2 rec.
           |   |__endolysosome membrane 3 rec.
           |   |__lumenal side of lysosomal membrane
           |   |__lysosomal HOPS complex 1 rec.
           |   |__lysosomal proton-transporting V-type ATPase complex(+)
           |   |__phagolysosome membrane
           |__lysosomal multienzyme complex
           |__mast cell granule
           |__megasome
           |__primary lysosome
           |   |__azurophil granule(+)
           |__secondary lysosome 34 rec.
           |   |__autolysosome(+) 32 rec.
           |   |__phagolysosome(+) 2 rec.
           |__UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex
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NIF_Subcellular:sao585356902
Wikipedia:Lysosome