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General Information
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| Term |
eukaryotic translation initiation factor 3 complex |
ID (Ontology) |
GO:0005852 (Gene Ontology) |
| Definition |
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.[ PubMed:15904532 ] |
| Also Known As |
"eIF-3" ; "eIF3" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 16 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes |
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eukaryotic translation initiation factor 3 complex (all annotations which use CV term, excluding "NOT" statements) | 16 | part_of | eukaryotic translation initiation factor 3 complex | 16 |
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Relationships
