FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cytoskeleton ID (Ontology) GO:0005856 (Gene Ontology)
Definition A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.[ PubMed:16959967 PubMed:27419875 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       7
Genes (FBgn)  GO_CELLULAR_COMPONENT      43
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 cytoskeleton (all annotations which use CV term, excluding "NOT" statements)       7     43      4
     cytoskeleton | embryonic stage       1       --       --
     cytoskeleton | embryonic stage | germline clone       2       --       --
     cytoskeleton | germline clone       2       --       --
     cytoskeleton | larval stage       2       --       1
     cytoskeleton | oogenesis       3       --       3
     cytoskeleton | P-stage       3       --       2
     cytoskeleton | somatic clone       1       --       --
     is_active_in | cytoskeleton       --      26       --
     located_in | cytoskeleton       --      18       --
Spanning Tree (Parents/Children)
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membraneless organelle___
intracellular organelle__|
                         intracellular membraneless organelle
                          |__cytoskeleton  1546 rec.
                              |__actin cytoskeleton 405 rec.
                              |   |__postsynaptic actin cytoskeleton(+)
                              |   |__presynaptic actin cytoskeleton
                              |__cortical cytoskeleton 67 rec.
                              |   |__cortical actin cytoskeleton(+) 46 rec.
                              |   |__cortical microtubule cytoskeleton 4 rec.
                              |   |__cytoskeleton of presynaptic active zone(+) 13 rec.
                              |__intermediate filament cytoskeleton 5 rec.
                              |   |__neurofilament cytoskeleton
                              |   |__postsynaptic intermediate filament cytoskeleton
                              |   |__presynaptic intermediate filament cytoskeleton
                              |__microtubule cytoskeleton 1019 rec.
                              |__perinuclear theca
                              |__postsynaptic cytoskeleton
                              |   |__cytoskeleton of dendritic spine(+)
                              |   |__postsynaptic actin cytoskeleton(+)
                              |   |__postsynaptic intermediate filament cytoskeleton
                              |   |__postsynaptic septin cytoskeleton
                              |   |__postsynaptic spectrin-associated cytoskeleton
                              |__presynaptic cytoskeleton 14 rec.
                              |   |__cytoskeleton of presynaptic active zone(+) 13 rec.
                              |   |__presynaptic actin cytoskeleton
                              |   |__presynaptic intermediate filament cytoskeleton
                              |__septin cytoskeleton 10 rec.
                              |   |__postsynaptic septin cytoskeleton
                              |   |__septin cap(+)
                              |   |__septin collar(+)
                              |   |__septin filament array(+)
                              |   |__septin ring(+) 5 rec.
                              |   |__split septin rings(+)
                              |__spectrin-associated cytoskeleton 1 rec.
                                  |__postsynaptic spectrin-associated cytoskeleton
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Is a intracellular membraneless organelle
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Wikipedia:Cytoskeleton