FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term intermediate filament ID (Ontology) GO:0005882 (Gene Ontology)
Definition A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.[ ISBN:0198506732 PubMed:17493611 PubMed:17551517 PubMed:7979242 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       1
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 Genes
 intermediate filament (all annotations which use CV term, excluding "NOT" statements)       1
     colocalizes_with | intermediate filament       1
Spanning Tree (Parents/Children)
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  supramolecular fiber
   |__polymeric cytoskeletal fiber
       |__intermediate filament  5 rec.
           |__glial filament
           |__keratin filament 1 rec.
           |__lamin filament 3 rec.
           |__neurofilament
           |__type III intermediate filament
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Is a polymeric cytoskeletal fiber
Part of intermediate filament cytoskeleton
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Synonyms
  • "intermediate filament associated protein" RELATED
    "type I intermediate filament associated protein" RELATED
    "type II intermediate filament associated protein" RELATED
Secondary IDs
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FMA:63851
NIF_Subcellular:sao952483289
Wikipedia:Intermediate_filament